Biomedical applications of polyelectrolyte coated spherical gold nanoparticles

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Date
2019-04-24
Authors
Fuller, Melanie A
Köper, Ingo
Journal Title
Journal ISSN
Volume Title
Publisher
Springer
Rights
© The Author(s) 2019
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The Author(s)
Abstract
Surface modified gold nanoparticles are becoming more and more popular for use in biomaterials due to the possibility for specific targeting and increased biocompatibility. This review provides a summary of the recent literature surrounding polyelectrolyte coatings on spherical gold nanoparticles and their potential biomedical applications. The synthesis and layer-by layer coating approach are briefly discussed together with common characterisation methods. The potential applications and recent developments in drug delivery, gene therapy, photothermal therapy and imaging are summarized as well as the effects on cellular uptake and toxicity. Finally, the future outlook for polyelectrolyte coated gold nanoparticles is explored, focusing on their use in biomedicine.
Description
© The Author(s) 2019 This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Keywords
Polyelectrolyte, Gold nanoparticles, Nanoparticles, Gold, Biomedical
Citation
Fuller, M. A., & Köper, I. (2019). Biomedical applications of polyelectrolyte coated spherical gold nanoparticles. Nano Convergence, 6(1). https://doi.org/10.1186/s40580-019-0183-4