Guidance framework for testing of genetically modified mosquitoes
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Date
2014-06
Authors
Benedict, Mark
Bonsall, Mike
James, Anthony A
James, Stephanie
Lavery, Jim
Mumford, John
Quemada, Hector
Rose, Robert
Thompson, Paul
Toure, Yeya
Journal Title
Journal ISSN
Volume Title
Publisher
World Health Organization
Rights
Copyright © World Health Organization on behalf of the Special Programme for Research and Training in Tropical Diseases 2014
Rights Holder
World Health Organization
Abstract
Commissioned by TDR and the Foundation for the National Institutes of Health (FNIH), this framework was drafted by four different working groups (efficacy; safety; ethical, legal and social; and regulation), each of which received comments about their draft from experts in the field and the public.
Genetically modified mosquitoes (GMM) engineered to be incapable of transmitting certain pathogens or able to reduce populations of similar native mosquito vectors have emerged as a promising new tool to combat vector-borne diseases like malaria and dengue in the more than 100 countries where they’re endemic.
The guidance framework aims to foster quality and consistency among processes for testing and regulating new genetic technologies by proposing standards of efficacy and safety testing comparable to those used for trials of other new public health tools.
The framework does not represent the views of the World Health Organization (WHO) or FNIH or provide recommendations on what to do. Rather, it is a document that brings together what is known, based on current research evidence, about how best to evaluate GMM.
Description
Reproduced in accordance with the publishers guidelines "The use of content from this health information product for all non-commercial education, training and information purposes is encouraged".
Keywords
Animals, Genetically Modified, genetics, Dengue, .Dengue - prevention and control., Malaria, Malaria - prevention and control., Mosquito, Mosquito Control, Insect Vectors
Citation
World Health Organization. (2014). Guidance framework for testing of genetically modified mosquitoes.