Assessing key safety concerns of a Wolbachia-based strategy to control dengue transmission by Aedes mosquitoes

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dc.contributor.authorPopovici, Jean
dc.contributor.authorMoreira, Luciano A
dc.contributor.authorPoinsignon, Anne
dc.contributor.authorIturbe-Ormaetxe, Inaki
dc.contributor.authorMcNaughton, Darlene
dc.contributor.authorO'Neill, Scott L
dc.date.accessioned2017-11-13T04:41:21Z
dc.date.available2017-11-13T04:41:21Z
dc.date.issued2010-12
dc.descriptionAll the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution Non-Commercial Licenseen
dc.description.abstractMosquito-borne diseases such as dengue fever, chikungunya or malaria affect millions of people each year and control solutions are urgently needed. An international research program is currently being developed that relies on the introduction of the bacterial endosymbiont Wolbachia pipientis into Aedes aegypti to control dengue transmission. In order to prepare for open-field testing releases of Wolbachia-infected mosquitoes, an intensive social research and community engagement program was undertaken in Cairns, Northern Australia. The most common concern expressed by the diverse range of community members and stakeholders surveyed was the necessity of assuring the safety of the proposed approach for humans, animals and the environment. To address these concerns a series of safety experiments were undertaken. We report in this paper on the experimental data obtained, discuss the limitations of experimental risk assessment and focus on the necessity of including community concerns in scientific research.en
dc.identifier.citationPopovici, J., Moreira, L. A., Poinsignon, A., Iturbe-Ormaetxe, I., McNaughton, D., & O’Neill, S. L. (2010). Assessing key safety concerns of a Wolbachia-based strategy to control dengue transmission by Aedes mosquitoes. Memórias Do Instituto Oswaldo Cruz, 105(8), 957–964. https://doi.org/10.1590/s0074-02762010000800002en
dc.identifier.doihttps://doi.org/10.1590/S0074-02762010000800002en
dc.identifier.issn0074-0276
dc.identifier.urihttp://hdl.handle.net/2328/37688
dc.language.isoen
dc.oaire.license.condition.licenseCC-BY-NC
dc.publisherScientific Electronic Library Onlineen
dc.rightsCC BY-NC The authorsen
dc.rights.holderThe authorsen
dc.subjectAedes aegyptien
dc.subjectWolbachiaen
dc.subjectdengueen
dc.subjectrisk assessmenten
dc.subjectsafetyen
dc.subjectbiological controlen
dc.titleAssessing key safety concerns of a Wolbachia-based strategy to control dengue transmission by Aedes mosquitoesen
dc.typeArticleen
local.contributor.authorOrcidLookupMcNaughton, Darlene: https://orcid.org/0000-0002-0131-5966en_US
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