Persistence of Ebola virus in ocular fluid during convalescence

Thumbnail Image
Varkey, Jay B
Shantha, Jessica G
Crozier, Ian
Kraft, Colleen S
Lyon, Marshall
Mehta, Aneesh K
Kumar, Gokul
Smith, Justine R
Kainulainen, Markus H
Whitmer, Shannon
Journal Title
Journal ISSN
Volume Title
Massachusetts Medical Society
Among the survivors of Ebola virus disease (EVD), complications that include uveitis can develop during convalescence, although the incidence and pathogenesis of EVD-associated uveitis are unknown. We describe a patient who recovered from EVD and was subsequently found to have severe unilateral uveitis during convalescence. Viable Zaire ebolavirus (EBOV) was detected in aqueous humor 14 weeks after the onset of EVD and 9 weeks after the clearance of viremia.
Please note: A correction to the original article has been published. “From New England Journal of Medicine, Jay B. Varkey, Jessica G. Shantha, Ian Crozier, Colleen S. Kraft, G. Marshall Lyon, Aneesh K. Mehta, Gokul Kumar, Justine R. Smith, Markus H. Kainulainen, Shannon Whitmer, Ute Ströher, Timothy M. Uyeki, Bruce S. Ribner, and Steven Yeh, Persistence of Ebola Virus in Ocular Fluid during Convalescence, 2015; 372:2423-2427. Copyright © (2015) Massachusetts Medical Society. Reprinted with permission.
Ophthalmology, Ebola virus
Varkey, J.B., Shantha, J.G., Crozier, I., Kraft, C.S., Lyon, M., Mehta, A.K., Kumar, G., Smith, J.R., Kainulainen, M.H., Whitmer, S., Stroher, U., Uyeki, T.M., Ribner, B.S. and Yeh, S., 2015. Persistence of Ebola virus in ocular fluid during convalescence. The New England Journal of Medicine, 372, 2423-2427.