The "Albumin Effect" and in Vitro-in
Vivo Extrapolation: Sequestration of Long-Chain Unsaturated Fatty Acids Enhances
Phenytoin Hydroxylation by Human Liver Microsomal and Recombinant Cytochrome P450
2C9
The "Albumin Effect" and in Vitro-in
Vivo Extrapolation: Sequestration of Long-Chain Unsaturated Fatty Acids Enhances
Phenytoin Hydroxylation by Human Liver Microsomal and Recombinant Cytochrome P450
2C9
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Date
2008
Authors
Mackenzie, Peter Ian
Miners, John Oliver
Rowland, Andrew
Elliot, David John
Knights, Kathleen Mary
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Citation
Rowland, A., Elliot, D.J., Knights, K.M.,
Mackenzie, P.I., & Miners, J.O., 2008. The "Albumin Effect" and in
Vitro-in Vivo Extrapolation: Sequestration of Long-Chain Unsaturated Fatty Acids
Enhances Phenytoin Hydroxylation by Human Liver Microsomal and Recombinant Cytochrome
P450 2C9. Drug Metabolism and Disposition, 36(5), 870-877.