Consumption of the Soluble Dietary Fibre Complex PolyGlycopleX® Reduces Glycaemia and Increases Satiety of a Standard Meal Postprandially

dc.contributor.author Solah, Vicky A
dc.contributor.author O'Mara-Wallace, Babette
dc.contributor.author Meng, Xingqiong (Rosie)
dc.contributor.author Gahler, Roland J
dc.contributor.author Kerr, Deborah A
dc.contributor.author James, Anthony P
dc.contributor.author Fenton, Haelee
dc.contributor.author Johnson, Stuart K
dc.contributor.author Wood, Simon
dc.date.accessioned 2016-09-07T00:35:34Z
dc.date.available 2016-09-07T00:35:34Z
dc.date.issued 2016
dc.description This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). en
dc.description.abstract The effect of consumption of PolyGlycopleX® (PGX®) was compared to wheat dextrin (WD) in combination with a standard meal, on postprandial satiety and glycaemia in a double-blind, randomised crossover trial, of 14 healthy subjects trained as a satiety panel. At each of six two-hour satiety sessions, subjects consumed one of three different test meals on two separate occasions. The test meals were: a standard meal plus 5 g PGX; a standard meal plus 4.5 g of PGX as softgels; and a standard meal plus 5 g of WD. Subjects recorded fullness using a labelled magnitude scale at 0, 15, 30, 45, 60, 90, and 120 min and the total area under the curve (AUC), mean fullness vs. time was calculated. The meals with PGX (in granular and softgel form) gave higher satiety (AUC) (477 121 and 454 242 cm min), than the meal with WD (215 261 cm min) (p < 0.001). Subjects had blood glucose levels measured after the meals with PGX (granules) and WD. Glucose response (AUC) was significantly lower (p < 0.001) after the PGX meal than for the WD meal. The high viscosity reported for PGX is a likely mechanism behind the significant satiety and blood glucose modulating effects observed in this study. en
dc.identifier.citation Solah VA, O’Mara-Wallace B, Meng X, et al. Consumption of the Soluble Dietary Fibre Complex PolyGlycopleX® Reduces Glycaemia and Increases Satiety of a Standard Meal Postprandially. Nutrients. 2016;8(5):268. doi:10.3390/nu8050268. en
dc.identifier.doi https://doi.org/10.3390/nu8050268 en
dc.identifier.issn 2072-6643
dc.identifier.uri http://hdl.handle.net/2328/36380
dc.language.iso en
dc.oaire.license.condition.license CC-BY
dc.publisher MDPI en
dc.rights Copyright © 2016 by the authors; licensee MDPI, Basel, Switzerland. en
dc.rights.holder The Authors en
dc.subject PGX en
dc.subject dextrin en
dc.subject glycaemia en
dc.subject fibre en
dc.subject satiety en
dc.title Consumption of the Soluble Dietary Fibre Complex PolyGlycopleX® Reduces Glycaemia and Increases Satiety of a Standard Meal Postprandially en
dc.type Article en
local.contributor.authorOrcidLookup Meng, Xingqiong (Rosie): https://orcid.org/0000-0001-8935-358X en_US
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