End-of-life research: do we need to build proxy consent into all clinical trial protocols studying the terminal phase?

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Date
2012-09-04
Authors
Sheehan, Caitlin
Agar, Meera Ruth
Currow, David Christopher
Journal Title
Journal ISSN
Volume Title
Publisher
Mary Ann Liebert, Inc.
Rights
Rights Holder
© Mary Ann Liebert, Inc.
Abstract
Research into symptoms that occur at the end of life is paramount for ensuring we provide the best possible care for patients in the terminal phase, yet obtaining informed consent from the study participant is not possible at the time these symptoms occur. Importantly, these questions cannot be answered in any clinical population and defining the net clinical effect of medications used, for example, for noisy respiratory secretions is crucial if the quality of care is to be further improved.
Description
Keywords
Palliative care, Clinical Pharmacology
Citation
Sheehan, C., Agar, M.R. and Currow, D.C., 2012. End-of-life research: do we need to build proxy consent into all clinical trial protocols studying the terminal phase? Journal of Palliative Medicine, 15(9), 962.