Prevention of Type 2 Diabetes by lifestyle intervention in an Australian primary health care setting: Greater Green Triangle (GGT) Diabetes Prevention Project

dc.contributor.author Laatikainen, Tiina K M
dc.contributor.author Dunbar, James Anthony
dc.contributor.author Chapman, Anna Kristina
dc.contributor.author Kilkkinen, Annamari
dc.contributor.author Vartiainen, Erkki
dc.contributor.author Heistaro, Sami Mikael
dc.contributor.author Philpot, Benjamin Joel
dc.contributor.author Absetz, Pilvikki
dc.contributor.author Bunker, Stephen
dc.contributor.author O'Neil, Adrienne Elizabeth
dc.contributor.author Reddy, Prasuna
dc.contributor.author Best, James D
dc.contributor.author Janus, Edward Denis
dc.date.accessioned 2008-09-30T05:12:05Z
dc.date.available 2008-09-30T05:12:05Z
dc.date.issued 2007-09-19
dc.description Trial Number Current Controlled Trials ISRCTN38031372 en
dc.description.abstract Background Randomised controlled trials demonstrate a 60% reduction in type 2 diabetes incidence through lifestyle modification programmes. The aim of this study is to determine whether such programmes are feasible in primary health care. Methods An intervention study including 237 individuals 40–75 years of age with moderate or high risk of developing type 2 diabetes. A structured group programme with six 90 minute sessions delivered during an eight month period by trained nurses in Australian primary health care in 2004–2006. Main outcome measures taken at baseline, three, and 12 months included weight, height, waist circumference, fasting plasma glucose and lipids, plasma glucose two hours after oral glucose challenge, blood pressure, measures of psychological distress and general health outcomes. To test differences between baseline and follow-up, paired t-tests and Wilcoxon rank sum tests were performed. Results At twelve months participants' mean weight reduced by 2.52 kg (95% confidence interval 1.85 to 3.19) and waist circumference by 4.17 cm (3.48 to 4.87). Mean fasting glucose reduced by 0.14 mmol/l (0.07 to 0.20), plasma glucose two hours after oral glucose challenge by 0.58 mmol/l (0.36 to 0.79), total cholesterol by 0.29 mmol/l (0.18 to 0.40), low density lipoprotein cholesterol by 0.25 mmol/l (0.16 to 0.34), triglycerides by 0.15 mmol/l (0.05 to 0.24) and diastolic blood pressure by 2.14 mmHg (0.94 to 3.33). Significant improvements were also found in most psychological measures. Conclusion This study provides evidence that a type 2 diabetes prevention programme using lifestyle intervention is feasible in primary health care settings, with reductions in risk factors approaching those observed in clinical trials. en
dc.identifier.citation Laatikainen T, Dunbar JA, Chapman A, Kilkkinen A, Vartiainen E, Heistaro S, Philpot B, Absetz P, Bunker S, O'Neil A E, Reddy P, Best JD, Janus ED 2007 Prevention of Type 2 Diabetes by lifestyle intervention in an Australian primary health care setting: Greater Green Triangle (GGT) Diabetes Prevention Project. BMC Public Health 2007, 7:249 en
dc.identifier.issn 1471-2458
dc.identifier.uri http://hdl.handle.net/2328/3175
dc.language.iso en
dc.publisher BioMed Central - http://www.biomedcentral.com en
dc.rights.license CC-BY
dc.subject *Diabetes Mellitus, Type 2 -- Prevention & Control en
dc.subject Health Promotion -- Methods en
dc.subject Rural Health Services en
dc.title Prevention of Type 2 Diabetes by lifestyle intervention in an Australian primary health care setting: Greater Green Triangle (GGT) Diabetes Prevention Project en
dc.type Article en
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