Sleep apnea cardiovascular clinical trials - current status and steps forward: the International Collaboration of Sleep Apnea Cardiovascular Trialists

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dc.contributor.author Gottlieb, Daniel J
dc.contributor.author Craig, Sonya E
dc.contributor.author Lorenzi-Filho, Geraldo
dc.contributor.author Heeley, Emma
dc.contributor.author Redline, Susan
dc.contributor.author McEvoy, Ronald Douglas
dc.contributor.author Duran-Cantolla, Joaquin
dc.date.accessioned 2013-08-21T00:23:23Z
dc.date.available 2013-08-21T00:23:23Z
dc.date.issued 2013-02
dc.description.abstract Sleep apnea is a common chronic disease that is associated with coronary heart disease, stroke, heart failure and mortality, although the ability of sleep apnea treatment to reduce cardiovascular morbidity and mortality has not been demonstrated. In contrast to patients seeking treatment in sleep disorders centers, as many as half of individuals with moderate to severe sleep apnea in the general population do not report excessive sleepiness; however, if treatment of sleep apnea were shown to reduce cardiovascular disease risk, this would provide a strong rationale for treatment of sleep apnea even in the absence of daytime sleepiness. This article summarizes the status of clinical trials evaluating the potential cardiovascular benefits of sleep apnea treatment and discusses the challenges of conducting such trials, and introduces the International Collaboration of Sleep Apnea Cardiovascular Trialists (INCOSACT), a clinical research collaboration formed to foster cardiovascular sleep research. en
dc.description.sponsorship Australian National Health and Medical Research Council en
dc.identifier.citation Gottlieb, D.J., Craig, S.E., Lorenzi-Filho, G., Heeley, E., Redline, S., McEvoy, R.D. and Durán-Cantolla, J., 2013. Sleep apnea cardiovascular clinical trials— current status and steps forward: the International Collaboration of Sleep Apnea Cardiovascular Trialists. Sleep, 36(7), 975-980. en
dc.identifier.doi https://doi.org/10.5665/sleep.2790 en
dc.identifier.issn 0161-8105
dc.identifier.uri http://hdl.handle.net/2328/26974
dc.language.iso en
dc.oaire.license.condition.license In Copyright
dc.publisher American Academy of Sleep Medicine en
dc.relation http://purl.org/au-research/grants/nhmrc/1006501 en
dc.relation.grantnumber NHMRC/1006501 en
dc.rights.holder © Copyright 2013 Associated Professional Sleep Societies, LLC en
dc.subject Sleep apnea en
dc.subject Sleep study en
dc.subject Treatment en
dc.subject Cardiovascular morbidity en
dc.subject Sleep Research en
dc.title Sleep apnea cardiovascular clinical trials - current status and steps forward: the International Collaboration of Sleep Apnea Cardiovascular Trialists en
dc.type Article en
local.contributor.authorOrcidLookup McEvoy, Ronald Douglas: https://orcid.org/0000-0002-5759-0094 en_US
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