Prevalence and type of artefact with spectral domain optical coherence tomography macular ganglion cell imaging in glaucoma surveillance

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dc.contributor.authorAwadalla, Mona Sen_US
dc.contributor.authorFitzgerald, Jude Ten_US
dc.contributor.authorAndrew, Nicholas Hen_US
dc.contributor.authorZhou, Tigeren_US
dc.contributor.authorMarshall, Henryen_US
dc.contributor.authorQassim, Ayuben_US
dc.contributor.authorHassall, Marken_US
dc.contributor.authorCasson, Robert Jen_US
dc.contributor.authorGraham, Stuart Len_US
dc.contributor.authorHealey, Paul Ren_US
dc.contributor.authorAgar, Ashishen_US
dc.contributor.authorGalanopoulos, Annaen_US
dc.contributor.authorPhipps, Simonen_US
dc.contributor.authorChappell, Angela Jen_US
dc.contributor.authorLanders, Johnen_US
dc.contributor.authorCraig, Jamie Een_US
dc.date.accessioned2019-02-26T03:54:41Z
dc.date.available2019-02-26T03:54:41Z
dc.date.issued2018-12-05
dc.descriptionCopyright: © 2018 Awadalla et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_US
dc.description.abstractPurpose The ganglion cell analysis (GCA) of the CIRRUSTM HD-OCT (Carl Zeiss, Meditec; Dublin, CA) provides measurement of the macular ganglion cell-inner plexiform layer (GCIPL) thickness. This study determined the frequency of scan artefacts and errors in GCIPL imaging in individuals undergoing HD-OCT surveillance for glaucoma. Method A total of 1439 eyes from 721 subjects enrolled in a prospective study assessing predictors of glaucoma progression underwent macular GCIPL imaging with the CIRRUS HD-OCT at recruitment. The prevalence of acquisition errors, segmentation errors, and co-morbid macular pathology was determined. Results A total of 87 (6.0%) of the 1439 scans had either acquisition errors, segmentation artefacts, or other macular pathology. The most common co-morbid macular pathology was epiretinal membrane in 2.2% of eyes. Conclusion The macular GCIPL scan was artefact free in 94% of eyes. However, epiretinal membrane and high myopia can cause scan artefact and should be considered when interpreting the results.en_US
dc.identifier.citationAwadalla MS, Fitzgerald J, Andrew NH, Zhou T, Marshall H, Qassim A, et al. (2018) Prevalence and type of artefact with spectral domain optical coherence tomography macular ganglion cell imaging in glaucoma surveillance. PLoS ONE 13(12): e0206684. https://doi.org/ 10.1371/journal.pone.0206684en_US
dc.identifier.doihttps://doi.org/10.1371/journal.pone.0206684
dc.identifier.issn1932-6203
dc.identifier.urihttp://hdl.handle.net/2328/39022
dc.language.isoenen_US
dc.oaire.license.condition.licenseCC-BY
dc.publisherPublic Library of Scienceen_US
dc.relationhttp://purl.org/au-research/grants/nhmrc/1048037en_US
dc.relationhttp://purl.org/au-research/grants/nhmrc/1065433en_US
dc.relation.grantnumberNHMRC/1048037en_US
dc.relation.grantnumberNHMRC/1065433en_US
dc.rightsCopyright: © 2018 Awadalla et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_US
dc.rights.holderAwadalla et al.en_US
dc.subjectganglion cell analysis (GCA)en_US
dc.subjectganglion cell-inner plexiform layer (GCIPL) thicknessen_US
dc.subjectacquisition erroren_US
dc.titlePrevalence and type of artefact with spectral domain optical coherence tomography macular ganglion cell imaging in glaucoma surveillanceen_US
dc.typeArticleen_US
local.contributor.authorOrcidLookupAwadalla, Mona S: https://orcid.org/0000-0002-7758-7669en_US
local.contributor.authorOrcidLookupMarshall, Henry: https://orcid.org/0000-0002-4425-2272en_US
local.contributor.authorOrcidLookupHassall, Mark: https://orcid.org/0000-0002-6180-7954en_US
local.contributor.authorOrcidLookupCraig, Jamie E: https://orcid.org/0000-0001-9955-9696en_US
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