Prevalence and type of artefact with spectral domain optical coherence tomography macular ganglion cell imaging in glaucoma surveillance

dc.contributor.author Awadalla, Mona S en_US
dc.contributor.author Fitzgerald, Jude T en_US
dc.contributor.author Andrew, Nicholas H en_US
dc.contributor.author Zhou, Tiger en_US
dc.contributor.author Marshall, Henry en_US
dc.contributor.author Qassim, Ayub en_US
dc.contributor.author Hassall, Mark en_US
dc.contributor.author Casson, Robert J en_US
dc.contributor.author Graham, Stuart L en_US
dc.contributor.author Healey, Paul R en_US
dc.contributor.author Agar, Ashish en_US
dc.contributor.author Galanopoulos, Anna en_US
dc.contributor.author Phipps, Simon en_US
dc.contributor.author Chappell, Angela J en_US
dc.contributor.author Landers, John en_US
dc.contributor.author Craig, Jamie E en_US
dc.date.accessioned 2019-02-26T03:54:41Z
dc.date.available 2019-02-26T03:54:41Z
dc.date.issued 2018-12-05
dc.description Copyright: © 2018 Awadalla et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. en_US
dc.description.abstract Purpose The ganglion cell analysis (GCA) of the CIRRUSTM HD-OCT (Carl Zeiss, Meditec; Dublin, CA) provides measurement of the macular ganglion cell-inner plexiform layer (GCIPL) thickness. This study determined the frequency of scan artefacts and errors in GCIPL imaging in individuals undergoing HD-OCT surveillance for glaucoma. Method A total of 1439 eyes from 721 subjects enrolled in a prospective study assessing predictors of glaucoma progression underwent macular GCIPL imaging with the CIRRUS HD-OCT at recruitment. The prevalence of acquisition errors, segmentation errors, and co-morbid macular pathology was determined. Results A total of 87 (6.0%) of the 1439 scans had either acquisition errors, segmentation artefacts, or other macular pathology. The most common co-morbid macular pathology was epiretinal membrane in 2.2% of eyes. Conclusion The macular GCIPL scan was artefact free in 94% of eyes. However, epiretinal membrane and high myopia can cause scan artefact and should be considered when interpreting the results. en_US
dc.identifier.citation Awadalla MS, Fitzgerald J, Andrew NH, Zhou T, Marshall H, Qassim A, et al. (2018) Prevalence and type of artefact with spectral domain optical coherence tomography macular ganglion cell imaging in glaucoma surveillance. PLoS ONE 13(12): e0206684. https://doi.org/ 10.1371/journal.pone.0206684 en_US
dc.identifier.doi https://doi.org/10.1371/journal.pone.0206684
dc.identifier.issn 1932-6203
dc.identifier.uri http://hdl.handle.net/2328/39022
dc.language.iso en en_US
dc.publisher Public Library of Science en_US
dc.relation http://purl.org/au-research/grants/nhmrc/1048037 en_US
dc.relation http://purl.org/au-research/grants/nhmrc/1065433 en_US
dc.relation.grantnumber NHMRC/1048037 en_US
dc.relation.grantnumber NHMRC/1065433 en_US
dc.rights Copyright: © 2018 Awadalla et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. en_US
dc.rights.holder Awadalla et al. en_US
dc.rights.license CC-BY
dc.subject ganglion cell analysis (GCA) en_US
dc.subject ganglion cell-inner plexiform layer (GCIPL) thickness en_US
dc.subject acquisition error en_US
dc.title Prevalence and type of artefact with spectral domain optical coherence tomography macular ganglion cell imaging in glaucoma surveillance en_US
dc.type Article en_US
local.contributor.authorOrcidLookup Awadalla, Mona S: https://orcid.org/0000-0002-7758-7669 en_US
local.contributor.authorOrcidLookup Marshall, Henry: https://orcid.org/0000-0002-4425-2272 en_US
local.contributor.authorOrcidLookup Hassall, Mark: https://orcid.org/0000-0002-6180-7954 en_US
local.contributor.authorOrcidLookup Craig, Jamie E: https://orcid.org/0000-0001-9955-9696 en_US
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