Early supported discharge by caregiver-mediated exercises and e-health support after stroke - a proof of concept trial

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Date
2016-07
Authors
van den Berg, Maayken
Crotty, Maria
Liu, Enwu
Killington, Maggie
Kwakkel, G
van Wegen, E
Journal Title
Journal ISSN
Volume Title
Publisher
American Heart Association, Inc
Rights
© 2016 American Heart Association, Inc.
Rights Holder
American Heart Association, Inc.
Abstract
Background and Purpose—: This proof-of-concept trial investigated the effects of an 8-week program of caregiver-mediated exercises commenced in hospital combined with tele-rehabilitation services on patient self-reported mobility and caregiver burden. Methods—: Sixty-three hospitalized stroke patients (mean age 68.7, 64% female) were randomly allocated to an 8-week caregiver-mediated exercises program with e-health support or usual care. Primary outcome was the Stroke Impact Scale mobility domain. Secondary outcomes included length of stay, other Stroke Impact Scale domains, readmissions, motor impairment, strength, walking ability, balance, mobility, (extended) activities of daily living, psychosocial functioning, self-efficacy, quality of life, and fatigue. Additionally, caregiver’s self-reported fatigue, symptoms of anxiety, self-efficacy, and strain were assessed. Assessments were completed at baseline and at 8 and 12 weeks. Results—: Intention-to-treat analysis showed no between-group difference in Stroke Impact Scale mobility (P=0.6); however, carers reported less fatigue (4.6, confidence interval [CI] 95% 0.3–8.8; P=0.04) and higher self-efficacy (-3.3, CI 95% -5.7 to -0.9; P=0.01) at week 12. Per-protocol analysis, examining those who were discharged home with tele-rehabilitation demonstrated a trend toward improved mobility (-9.8, CI 95% -20.1 to 0.4; P=0.06), significantly improved extended activities of daily living scores at week 8 (-3.6, CI 95% -6.3 to -0.8; P=0.01) and week 12 (3.0, CI 95% -5.8 to -0.3; P=0.03), a 9-day shorter length of stay (P=0.046), and fewer readmissions over 12 months (P<0.05). Conclusions—: Caregiver-mediated exercises supported by tele-rehabilitation show promise to augment intensity of practice, resulting in improved patient-extended activities of daily living, reduced length of stay with fewer readmissions post stroke, and reduced levels of caregiver fatigue with increased feelings of self-efficacy. The current findings justify a larger definite phase III randomized controlled trial.
Description
Embargoed by publisher until 31 Dec 2016
Keywords
Stroke, telemedicine, exercise, aregiver-mediated exercises, e-health, home rehabilitation, Rehabilitation, Cerebrovascular Disease/Stroke
Citation
Van den Berg, M., Crotty, M., Liu, E., Killington, M., Kwakkel, G., & Van Wegen, E. (2016). Early Supported Discharge by Caregiver-Mediated Exercises and e-Health Support After Stroke: A Proof-of-Concept Trial. Stroke, 47(7), 1885-1892.