The Linoleic Acid: Dihomo-γ-Linolenic Acid Ratio (LA:DGLA)—An Emerging Biomarker of Zn Status

dc.contributor.authorKnez, Marija
dc.contributor.authorStangoulis, James Constantine Roy
dc.contributor.authorGlibetic, Maria
dc.contributor.authorTako, Elad
dc.date.accessioned2017-09-22T00:30:09Z
dc.date.available2017-09-22T00:30:09Z
dc.date.issued2017-08-01
dc.descriptionLicensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).en
dc.description.abstractZinc (Zn) deficiency is a common aliment predicted to affect 17% of the world’s population. Zinc is a vital micronutrient used for over 300 enzymatic reactions and multiple biochemical and structural processes in the body. Although whole blood, plasma, and urine zinc decrease in severe zinc deficiency, accurate assessment of zinc status, especially in mild to moderate deficiency, is difficult as studies with these biomarkers are often contradictory and inconsistent. Hence, as suggested by the World Health Organization, sensitive and specific biological markers of zinc status are still needed. In this review, we provide evidence to demonstrate that the LA:DGLA ratio (linoleic acid:dihomo-γ-linolenic acid ratio) may be a useful additional indicator for assessing Zn status more precisely. However, this biomarker needs to be tested further in order to determine its full potential. View Full-Texten
dc.identifier.citationShavrukov Y, Zhumalin A, Serikbay D, Botayeva M, Otemisova A, Absattarova A, Sereda G, Sereda S, Shvidchenko V, Turbekova A, Jatayev S, Lopato S, Soole K and Langridge P (2016) Expression Level of the DREB2-Type Gene, Identified with Amplifluor SNP Markers, Correlates with Performance, and Tolerance to Dehydration in Bread Wheat Cultivars from Northern Kazakhstan. Front. Plant Sci. 7:1736. doi: 10.3389/fpls.2016.01736en
dc.identifier.doihttps://doi.org/10.3390/nu9080825en
dc.identifier.issn2072-6643
dc.identifier.urihttp://hdl.handle.net/2328/37498
dc.language.isoen
dc.oaire.license.condition.licenseCC-BY
dc.publisherMDPIen
dc.rights© 2017 by the authors.en
dc.rights.holderthe authors.en
dc.subjectbiomarkeren
dc.subjectZnen
dc.subjectZincen
dc.subjectLA:DGLAen
dc.subjectZn statusen
dc.subjectfatty aciden
dc.titleThe Linoleic Acid: Dihomo-γ-Linolenic Acid Ratio (LA:DGLA)—An Emerging Biomarker of Zn Statusen
dc.typeArticleen
local.contributor.authorOrcidLookupStangoulis, James Constantine Roy: https://orcid.org/0000-0001-7778-7110en_US
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