New insights into the viscoelastic and failure mechanical properties of the elastic fiber network of the inter-lamellar matrix in the annulus fibrosus of the disc

dc.contributor.authorTavakoli, Javad
dc.contributor.authorCosti, John Jack
dc.date.accessioned2018-08-23T02:32:00Z
dc.date.available2018-08-23T02:32:00Z
dc.date.issued2018-07-10
dc.descriptionPublished by Elsevier Ltd. All rights reserved. This manuscript version is made available under the CC-BY-NCND 4.0 license: http://creativecommons.org/licenses/by-nc-nd/4.0/ This author accepted manuscript is made available following 24 month embargo from date of publication (Sept 2020) in accordance with the publisher’s archiving policyen_US
dc.description.abstractThe mechanical role of elastic fibers in the inter-lamellar matrix (ILM) is unknown; however, it has been suggested that they play a role in providing structural integrity to the annulus fibrosus (AF). Therefore, the aim of this study was to measure the viscoelastic and failure properties of the elastic fiber network in the ILM of ovine discs under both tension and shear directions of loading. Utilizing a technique, isolated elastic fibers within the ILM from ovine discs were stretched to 40% of their initial length at three strain rates of 0.1% s−1 (slow), 1% s−1 (medium) and 10% s−1 (fast), followed by a ramp test to failure at 10% s−1. A significant strain-rate dependent response was found, particularly at the fastest rate for phase angle and normalized stiffness (p < 0.001). The elastic fibers in the ILM demonstrated a significantly higher capability for energy absorption at slow compared to medium and fast strain rates (p < 0.001). These finding suggests that the elastic fiber network of the ILM exhibits nonlinear elastic behavior. When tested to failure, a significantly higher normalized failure force was found in tension compared to shear loading (p = 0.011), which is consistent with the orthotropic structure of elastic fibers in the ILM. The results of this study confirmed the mechanical contribution of the elastic fiber network to the ILM and the structural integrity of the AF. This research serves as a foundation for future studies to investigate the relationship between degeneration and ILM mechanical properties.en_US
dc.identifier.citationTavakoli, J., & Costi, J. J. (2018). New insights into the viscoelastic and failure mechanical properties of the elastic fiber network of the inter-lamellar matrix in the annulus fibrosus of the disc. Acta Biomaterialia, 77, 292– 300.en_US
dc.identifier.doihttps://doi.org/10.1016/j.actbio.2018.07.023en
dc.identifier.issn1742-7061
dc.identifier.urihttp://hdl.handle.net/2328/38208
dc.language.isoenen_US
dc.oaire.license.condition.licenseCC-BY-NC-ND
dc.publisherElsevieren_US
dc.rights© 2018 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved. This manuscript version is made available under the CC-BY-NCND 4.0 license: http://creativecommons.org/licenses/by-nc-nd/4.0/en_US
dc.rights.holder© 2018 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.en_US
dc.subjectInter-lamellar matrixen_US
dc.subjectelastic fibersen_US
dc.subjectannulus fibrosusen_US
dc.subjectmechanical propertyen_US
dc.subjectmaterial propertyen_US
dc.subjectovine modelen_US
dc.titleNew insights into the viscoelastic and failure mechanical properties of the elastic fiber network of the inter-lamellar matrix in the annulus fibrosus of the discen_US
dc.typeArticleen
local.contributor.authorOrcidLookupTavakoli, Javad: https://orcid.org/0000-0002-0696-6530en_US
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Tavakoli_New_AM2018.pdf
Size:
1.31 MB
Format:
Adobe Portable Document Format
Description:
Author manuscript
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.84 KB
Format:
Item-specific license agreed upon to submission
Description: