Number of People Blind or Visually Impaired by Glaucoma Worldwide and in World Regions 1990 - 2010: A Meta-Analysis

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dc.contributor.author Bourne, Rupert R A
dc.contributor.author Taylor, Hugh R
dc.contributor.author Flaxman, Seth R
dc.contributor.author Keeffe, Jill E
dc.contributor.author Leasher, Janet
dc.contributor.author Naidoo, Kovin
dc.contributor.author Pesudovs, Konrad
dc.contributor.author White, Richard A
dc.contributor.author Wong, T Y
dc.contributor.author Resnikoff, Serge
dc.contributor.author Jonas, Jost B
dc.contributor.author Vision Loss Expert Group of the Global Burden of Disease Study
dc.date.accessioned 2016-11-29T23:20:36Z
dc.date.available 2016-11-29T23:20:36Z
dc.date.issued 2016-10-20
dc.description This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. en
dc.description.abstract Objective To assess the number of individuals visually impaired or blind due to glaucoma and to examine regional differences and temporal changes in this parameter for the period from 1990 to 2012. Methods As part of the Global Burden of Diseases (GBD) Study 2010, we performed a systematic literature review for the period from 1980 to 2012. We primarily identified 14,908 relevant manuscripts, out of which 243 high-quality, population-based studies remained after review by an expert panel that involved application of selection criteria that dwelt on population representativeness and clarity of visual acuity methods used. Sixty-six specified the proportion attributable to glaucoma. The software tool DisMod-MR (Disease Modeling–Metaregression) of the GBD was used to calculate fraction of vision impairment due to glaucoma. Results In 2010, 2.1 million (95% Uncertainty Interval (UI):1.9,2.6) people were blind, and 4.2 (95% UI:3.7,5.8) million were visually impaired due to glaucoma. Glaucoma caused worldwide 6.6% (95% UI:5.9,7.9) of all blindness in 2010 and 2.2% (95% UI:2.0,2.8) of all moderate and severe visual impairment (MSVI). These figures were lower in regions with younger populations (<5% in South Asia) than in high-income regions with relatively old populations (>10%). From 1990 to 2010, the number of blind or visually impaired due to glaucoma increased by 0.8 million (95%UI:0.7, 1.1) or 62% and by 2.3 million (95%UI:2.1,3.5) or 83%, respectively. Percentage of global blindness caused by glaucoma increased between 1990 and 2010 from 4.4% (4.0,5.1) to 6.6%. Age-standardized prevalence of glaucoma related blindness and MSVI did not differ markedly between world regions nor between women. Significance By 2010, one out of 15 blind people was blind due to glaucoma, and one of 45 visually impaired people was visually impaired, highlighting the increasing global burden of glaucoma. en
dc.identifier.citation Bourne RRA, Taylor HR, Flaxman SR, Keeffe J, Leasher J, Naidoo K, et al. (2016) Number of People Blind or Visually Impaired by Glaucoma Worldwide and in World Regions 1990 ± 2010: A Meta-Analysis. PLoS ONE 11(10): e0162229. doi:10.1371/journal.pone.0162229 en
dc.identifier.doi https://doi.org/10.1371/journal.pone.0162229 en
dc.identifier.issn 1932-6203
dc.identifier.uri http://hdl.handle.net/2328/36784
dc.language.iso en
dc.oaire.license.condition.license CC-BY
dc.publisher Public Library of Science en
dc.rights © 2016 Bourne et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. en
dc.rights.holder The authors en
dc.subject Glaucoma en
dc.subject Blindness en
dc.subject Visual impairments en
dc.subject Visual acuity en
dc.subject Cataracts en
dc.subject Global health en
dc.subject Macular degeneration en
dc.subject Meta-analysis en
dc.title Number of People Blind or Visually Impaired by Glaucoma Worldwide and in World Regions 1990 - 2010: A Meta-Analysis en
dc.type Article en
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