1112 - Oncology and Carcinogenesis
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This collection contains Flinders' research in Oncology and Carcinogenesis, as reported for ERA 2012.
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Item Problem-solving therapy for psychological distress in Japanese cancer patients: preliminary clinical experience from psychiatric consultations(2008) Okuyama, Toru; Furukawa, Toshi; Momino, Kanae; Akechi, Tatsuo; Motooka, Hiroko; Shiozaki, Mariko; Chen, Junwen; Hirai, KeiItem A randomised pilot of a self-help workbook intervention for breast cancer survivors(2010) Beatty, Lisa Jane; Oxlad, Melissa Jane; Koczwara, Bogda; Wade, Tracey DianeItem MicroRNAs: Predictors and modifiers of chemo- and radiotherapy in different tumour types(2010) Hummel, Richard; Hussey, Damian James; Haier, JorgItem Interval Fecal Immunochemical Testing in a Colonoscopic Surveillance Program Speeds Detection of Colorectal Neoplasia(2010) Lane, Joanne Michelle; Bampton, Peter Alexander; Bull, Jeffrey Allan; Morcom, Joylene Margaret; Good, Norm; Sandford, Jayne Judith; Chow, Elizabeth; Young, Graeme Paul; Smith, Alicia Therese; Cole, Stephen RussellItem Infancy of an Australian geriatric oncology program-characteristics of the first 200 patients(2010) To, Timothy H M; Okera, M; Prouse, J; Prowse, R J; Singhal, NimitItem Restoring endocrine response in breast cancer cells by inhibition of the sphingosine kinase-1 signaling pathway.(2009) Sukocheva, Olga Anatolyevna; Verrier, Emily; Xia, Pu; Wang, Lina; Vadas, Matthew AItem DNA Methylation of the ABO Promoter Underlies Loss of ABO Allelic Expression in a Significant Proportion of Leukemic Patients(2009) Hussey, Damian James; Bianco-Miotto, T; Day, Tanya Kate; O'Keefe, Denise S; Dobrovic, AlexanderBackground Loss of A, B and H antigens from the red blood cells of patients with myeloid malignancies is a frequent occurrence. Previously, we have reported alterations in ABH antigens on the red blood cells of 55% of patients with myeloid malignancies. Methodology/Principal Findings To determine the underlying molecular mechanisms of this loss, we assessed ABO allelic expression in 21 patients with ABH antigen loss previously identified by flow cytometric analysis as well as an additional 7 patients detected with ABH antigen changes by serology. When assessing ABO mRNA allelic expression, 6/12 (50%) patients with ABH antigen loss detected by flow cytometry and 5/7 (71%) of the patients with ABH antigen loss detected by serology had a corresponding ABO mRNA allelic loss of expression. We examined the ABO locus for copy number and DNA methylation alterations in 21 patients, 11 with loss of expression of one or both ABO alleles, and 10 patients with no detectable allelic loss of ABO mRNA expression. No loss of heterozygosity (LOH) at the ABO locus was observed in these patients. However in 8/11 (73%) patients with loss of ABO allelic expression, the ABO promoter was methylated compared with 2/10 (20%) of patients with no ABO allelic expression loss (P = 0.03). Conclusions/Significance We have found that loss of ABH antigens in patients with hematological malignancies is associated with a corresponding loss of ABO allelic expression in a significant proportion of patients. Loss of ABO allelic expression was strongly associated with DNA methylation of the ABO promoter.Item New endoscopic and surgical treatment options for early esophageal adenocarcinoma(2010) Gan, Susan; Watson, David IanItem Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1(2006) Albanese, Nathaniel; Wadham, Carol; Sukocheva, Olga Anatolyevna; Xia, Pu; Holmes, Andrew; Verrier, Emily; Feng, Feng; Bernal, Alex; Derian, Claudia; Ullrich, Axel; Vadas, Matthew AItem Symptoms, investigations and management of patients with cancer of the oesophagus and gastro-oesophageal junction in Australia(2010) Smithers, B Mark; Fahey, Paul P; Corish, Tracie; Gotley, David C; Falk, Gregory L; Smith, Garrett; Kiroff, G; Clouston, Andrew D; Watson, David Ian; Whiteman, David CItem Palliative care compassion, care and complexity(2010) Agar, Meera RuthItem Management of refractory dyspnoea evidence-based interventions(2010) Davidson, Patricia; Currow, David ChristopherItem Nutritional Status and Information Needs of Medical Oncology Patients Receiving Treatment at an Australian Public Hospital(2010) Isenring, Elisabeth; Cross, Giordana; Daniels, Lynne Allison; Kellett, Elizabeth; Koczwara, BogdaItem Analysis of a set of missense, frameshift, and in-frame deletion variants of BRCA1(2009) Grist, Scott Andrew; Beddor, Jennifer; Pino, Maria A; Carvalho, Marcelo; Mesquita, Rafael D; Billack, Blase; Karchin, Rachel; Godinho-Netto, Martha; Rodarte, Renato S; Colombo, Mara; Ripamonti, Carla B; Rosenquist, Richard; Suthers, Graeme; Radice, Paolo; Monteiro, Alvaro N A; Monteiro, Viviane A; Manoukian, Siranoush; Borg, AkeItem Delirium in advanced cancer(2010) Sanderson, Christine Ruth; Agar, Meera RuthItem MicroRNA profiling of Barrett's oesophagus and oesophageal adenocarcinoma.(2010) Smith, Cameron; Michael, Michael Zenon; Wijnhoven, Bas; Hussey, Damian James; Watson, David Ian; Tsykin, AnnaItem Patients with chronic myeloid leukemia who maintain a complete molecular response after stopping imatinib treatment have evidence of persistent leukemia by DNA PCR(2010) Branford, S; Seymour, J F; Schwarer, A P; Arthur, C; Bartley, Paul Anthony; Slader, C; Field, C; Dang, P; Filshie, R J; Mills, A K; Grigg, A P; Melo, Junia; Hughes, Timothy P; Ross, David MorrallItem Rapid isolation of translocation breakpoints in chronic myeloid and acute promyelocytic leukaemia(2010) Ross, David Morrall; Bartley, Paul Anthony; Martin-Harris, Michael Henry; Budgen, Bradley John; Morley, Alexander AlanItem Sensitive detection and quantification of minimal residual disease in chronic myeloid leukaemia using nested quantitative PCR for BCR-ABL DNA(2010) Ross, David Morrall; Martin-Harris, Michael Henry; Budgen, Bradley John; Wilczek, Vicki Jane; Branford, S; Bartley, Paul Anthony; Latham, Susan Elizabeth; Hughes, Timothy P; Morley, Alexander AlanItem MiRNAs, development of Barrett's esophagus, and progression to esophageal adenocarcinoma.(2010) Smith, Cameron; Michael, Michael Zenon; Watson, David Ian; Hussey, Damian James