1103 - Clinical Sciences

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This collection contains Flinders' research in Clinical Sciences, as reported for ERA 2012.

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Now showing 1 - 6 of 585
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    Change in quality of life and their predictors in the long-term follow-up after group cognitive behavioural therapy for social anxiety disorder: A prospective cohort study
    ( 2010) Furukawa, Toshi ; Watanabe, Norio ; Chen, Junwen ; Nakano, Yumi ; Kinoshita, Yoshihiro ; Ietsugu, Tetsuji ; Ogawa, Sei ; Funayama, Tadashi ; Noda, Yumiko
    Background : Social anxiety disorder (SAD) is one of the most common anxiety disorders. The efficacy of cognitive behaviour therapy (CBT) has been examined but to date its effects on Quality of Life (QoL) have not been appropriately evaluated especially in the long term. The study aimed to examine, in the long term, what aspects of Quality of Life (QoL) changed among social anxiety disorder (SAD) patients treated with group cognitive behaviour therapy (CBT) and what predictors at baseline were associated with QoL. Methods : Outpatients diagnosed with SAD were enrolled into group CBT, and assessed at follow-ups for up to 12 months in a typical clinical setting. QoL was evaluated using the Short Form 36. Various aspects of SAD symptomatology were also assessed. Each of the QoL domains and scores on symptomatology were quantified and compared with those at baseline. Baseline predictors of QoL outcomes at follow-up were investigated. Results : Fifty-seven outpatients were enrolled into group CBT for SAD, 48 completed the whole program, and 44 and 40 completed assessments at the 3-month and 12-month follow-ups, respectively. All aspects of SAD symptomatology and psychological subscales of the QoL showed statistically significant improvement throughout follow-ups for up to 12 months. In terms of social functioning, no statistically significant improvement was observed at either follow-up point except for post-treatment. No consistently significant pre-treatment predictors were observed. Conclusions : After group CBT, SAD symptomatology and some aspects of QoL improved and this improvement was maintained for up to 12 months, but the social functioning domain did not prove any significant change statistically. Considering the limited effects of CBT on QoL, especially for social functioning, more powerful treatments are needed.
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    Sleep Well, Live Better : Three Steps to Good Sleep
    (Media21 Publishing Pty Ltd, 2010) Lack, Leon Colburn ; Wright, Helen
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    Impact of the HTR3A with early life trauma on emotional brain networks and depressed mood
    ( 2010) Clark, Christopher Richard ; Paul, Robert ; Grieve, Stuart ; Gordon, Evian ; Nemeroff, Charles ; Dobson-Stone, Carol ; Gatt, Justine M ; Williams, Leanne M ; Schofield, Peter R
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    The risk of falls and fractures associated with persistent use of psychotropic medications in elderly people
    ( 2010) Hoile, Annabel P ; Gilbert, Andrew ; Vitry, Agnes I ; Luszcz, Mary Alice ; Esterman, Adrian Jeffrey
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    What are the Mental Health needs of Adolescents in Rural South Australia? The Perceptions of Human Service Providers.
    ( 2009) Kurtin, Marijeta ; Winefield, Tony ; Edwards, Jane ; Barton, Christopher Allan
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    The choice of self-rated health measures matter when predicting mortality: Evidence from 10 years follow-up of the Australian longitudinal study of ageing
    ( 2010) Luszcz, Mary Alice ; Sargent-Cox, Kerry A ; Anstey, Kaarin Jane
    Background : Self-rated health (SRH) measures with different wording and reference points are often used as equivalent health indicators in public health surveys estimating health outcomes such as healthy life expectancies and mortality for older adults. Whilst the robust relationship between SRH and mortality is well established, it is not known how comparable different SRH items are in their relationship to mortality over time. We used a dynamic evaluation model to investigate the sensitivity of time-varying SRH measures with different reference points to predict mortality in older adults over time. Methods : We used seven waves of data from the Australian Longitudinal Study of Ageing (1992 to 2004; N = 1733, 52.6% males). Cox regression analysis was used to evaluate the relationship between three time-varying SRH measures (global, age-comparative and self-comparative reference point) with mortality in older adults (65+ years). Results : After accounting for other mortality risk factors, poor global SRH ratings increased mortality risk by 2.83 times compared to excellent ratings. In contrast, the mortality relationship with age-comparative and self-comparative SRH was moderated by age, revealing that these comparative SRH measures did not independently predict mortality for adults over 75 years of age in adjusted models. Conclusions : We found that a global measure of SRH not referenced to age or self is the best predictor of mortality, and is the most reliable measure of self-perceived health for longitudinal research and population health estimates of healthy life expectancy in older adults. Findings emphasize that the SRH measures are not equivalent measures of health status.