1114 - Paediatrics and Reproductive Medicine
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This collection contains Flinders' staff research in Paediatrics and Reproductive Medicine, reportable as part of Excellence in Research for Australia (ERA), from 2001-
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Browsing 1114 - Paediatrics and Reproductive Medicine by Subject "1103 Clinical Sciences"
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Item Activities of daily living in children with hemiplegic cerebral palsy: a cross-sectional evaluation using the Assessment of Motor and Process Skills(2006) Van Zelst, B R; Miller, Michelle Deanne; Russo, Remo Nunzio (Ray); Murchland, Sonya R; Crotty, MariaItem Amylase-resistant starch as adjunct to oral rehydration therapy in children with diarrhea(2006) Young, Graeme Paul; Binder, Henry J; Raghupathy, Palany; Ramakrishna, Balakrishnan S; Oommen, Samuel P; Ahmed, Mir S; Priyaa, G. Hari; Dziura, JamesItem Compared to placebo, long-term antibiotics resolve otitis media with effusion (OME) and prevent acute otitis media with perforation (AOMwiP) in a high-risk population: A randomized controlled trial(2008) Leach, Amanda Jane; Matthews, John D; Morris, Peter StanleyBackground : For children at high risk of chronic suppurative otitis media (CSOM), strategies to prevent acute otitis media with perforation (AOMwiP) may reduce progression to CSOM. Methods : In a double blind study in northern Australia, 103 Aboriginal infants with first detection of OME were randomised to receive either amoxicillin (50 mg/kg/d BD) or placebo for 24 weeks, or until bilateral aerated middle ears were diagnosed at two successive monthly examinations (success). Standardised clinical assessments and international standards for microbiology were used. Results : Five of 52 infants in the amoxicillin group and none of 51 infants in the placebo group achieved success at the end of therapy (Risk Difference = 9.6% [95% confidence interval 1.6,17.6]). Amoxicillin significantly reduced the proportion of children with i) perforation at the end of therapy (27% to 12% RD = -16% [-31,-1]), ii) recurrent perforation during therapy (18% to 4% RD = -14% [-25,-2]), and iii) reduced the proportion of examinations with a diagnosis of perforation during therapy (20% to 8% adjusted risk ratio 0.36 [0.15,0.83] p = 0.017). During therapy, the proportion of examinations with penicillin non-susceptible (MIC > 0.1 microg/ml) pneumococci was not significantly different between the amoxicillin group (34%) and the placebo group (40%). Beta-lactamase positive non-capsular H. influenzae (NCHi) were uncommon during therapy but more frequent in the amoxicillin group (10%) than placebo (5%). Conclusion : Aboriginal infants receiving continuous amoxicillin had more normal ears, fewer perforations, and less pneumococcal carriage. There was no statistically significant increase in resistant pneumococci or NCHi in amoxicillin children compared to placebo children who received regular paediatric care and antibiotic treatment for symptomatic illnesses.Item Double disadvantage: the influence of ethnicity over socioeconomic position on childhood overweight and obesity: findings from an inner urban population of primary school children(2008) O'Connor, Thea; Magarey, Anthea Margaret; Waters, Elizabeth; Ashbolt, R; Gibbons, Kay; Green, J; Lo, Sing Kai; Gold, Lisa; Garrard, J; Swinburn, Boyd A; Booth, Michael; Gibbs, LisaItem Effects of Blue Green Algal Toxin Cylindrospermopsin (CYN) on Human Granulosa Cells in vitro(2008) Young, Fiona Margaret; Micklem, Jasmine May; Humpage, Andrew RItem Effects of the insecticide amitraz, an alpha(2)-adrenergic receptor agonist, on human luteinized granulosa cells(2005) Young, Fiona Margaret; Menadue, Margaret F; Lavranos, Tina ChristineItem Embryo research: is disclosing commercial intent enough?(2006) De Lacey, Sheryl LynneItem Glucose control, organ failure, and mortality in pediatric intensive care(2008) Yung, Michael; Wilkins, Barry; Norton, Lynda; Slater, AnthonyItem Immunomodulatory constituents of human milk change in response to infant bronchiolitis(2007) Hart, Prue; Forsyth, Kevin Douglas; Gibson, Robert Alan; Bryan, Dani-Louise LouiseItem Laparoscopic paravaginal repair of anterior compartment prolapse(2007) Behnia-Willison, Fariba; Seman, Elvis Ivan; Cook, Jennifer Rachel; O'Shea, Robert Thomas; Keirse, Marc JozefItem Measuring quality of life in women with endometriosis: Tests of data quality, score reliability, response rate and scaling assumptions of the Endometriosis Health Profile Questionnaire(2006) Jenkinson, C; Jones, G; Taylor, Nik; Mills, A; Kennedy, SItem Parent identity and 'virtual' children: why patients discard rather than donate unused embryos(2005) De Lacey, Sheryl LynneItem Prevention of pertussis: recommendations derived from the second global pertussis initiative roundtable meeting(2007) Tan, Tina; Caro, Jaime; Plotkin, Stanley; Forsyth, Kevin Douglas; Wirsing von Knig, Carl-HeinzItem Randomised controlled trials in overweight children: practicalities and realities(2007) Okely, Anthony D; Jones, Rachel A; Morgan, Philip J; Baur, Louise A; Magarey, Anthea Margaret; Golley, Rebecca Kirsty; Warren, Janet M; Collins, Clare E; Steele, Julie R; Perry, Rebecca AnneItem A randomized controlled trial of glucose versus amylase resistant starch hypo-osmolar oral rehydration solution for adult acute dehydrating diarrhea(2008) Ramakrishna, Balakrishnan S; Sebastian, Bendon K; Young, Graeme Paul; Farthing, Michael; Binder, Henry J; Subramanian, Venkataraman; Mohan, VivekReduction of gross diarrhea rate in excess of that seen over time with intravenous therapy and appropriate antibiotics is not usually achieved by oral glucose-electrolyte rehydration therapy for cholera and cholera-like diarrheas. Methodology and Principal Findings This prospective randomized clinical trial at a tertiary referral hospital in southern India was undertaken to determine whether amylase resistant starch, substituting for glucose in hypo-osmolar oral rehydration solution, would reduce diarrhea duration and weight in adults with acute severe dehydrating diarrhea. 50 adult males with severe watery diarrhea of less than three days' duration and moderate to severe dehydration were randomized to receive hypo-osmolar ORS (HO-ORS) or HO-ORS in which amylase resistant high amylose maize starch 50g/L substituted for glucose (HAMS-ORS). All remaining therapy followed standard protocol. Duration of diarrhea (ORS commencement to first formed stool) in hours was significantly shorter with HAMS-ORS (median 19, IQR 10-28) compared to HO-ORS (median 42, IQR 24-50) (Bonferroni adjusted P, Padj<0.001). Survival analysis (Kaplan-Meier) showed faster recovery from diarrhea in the HAMS-ORS group (P<0.001, log rank test). Total diarrhea fecal weight in grams (median, IQR) was not significantly lower in the HAMS-ORS group (2190, 1160-5635) compared to HO-ORS (5210, 2095-12190) (Padj = 0.08). However, stool weight at 13-24 hours (280, 0-965 vs. 1360, 405-2985) and 25–48 hours (0, 0-360 vs. 1080, 55-3485) were significantly lower in HAMS-ORS compared to HO-ORS group (Padj = 0.048 and P = 0.012, respectively). ORS intake after first 24 hours was lower in the HAMS-ORS group. Subgroup analysis of patients with culture isolates of Vibrio cholerae indicated similar significant differences between the treatment groups.Item Restricted fetal growth and lung development: a morphometric analyses of pulmonary structure(2006) Lipsett, Jill; Tamblyn, Michelle; Madigan, Kellie; Roberts, Pam; Cool, Johanna C; Runciman, Susann Ines (Sue); McMillen, I Caroline; Robinson, Jeffrey; Owens, Julie AItem Self-esteem, self-concept, and quality of life in children with hemiplegic cerebral palsy(2008) Russo, Remo Nunzio (Ray); Goodwin, Emma Jane; Miller, Michelle Deanne; Connell, Timothy Minton; Crotty, Maria; Haan, Eric AlbertItem Sleep-disordered breathing in Prader-Willi syndrome and its association with neurobehavioral abnormalities(2005) O'Donoghue, Fergal James; Camfferman, Danny; Kennedy, J D; Martin, A J; Couper, T; Lack, Leon Colburn; Lushington, Kurt; McEvoy, Ronald DouglasItem Streptococcus pneumoniae and noncapsular Haemophilus influenzae nasal carriage and hand contamination in children: A comparison of two populations at risk of otitis media(2005) Stubbs, Elizabeth; Hare, Kim; Wilson, Cate; Morris, Peter Stanley; Leach, Amanda Jane